Query: NC_016938:1492486 Melissococcus plutonius DAT561 chromosome 1, complete genome
Lineage: Melissococcus plutonius; Melissococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: Causative agent of European foulbrood. Insect pathogen. Anaerobic or microaerophilic Gram-positive bacterium. European foulbrood is a disease of honeybee larvae, caused by the bacterium Melissococcus plutonius. It is found on all continents where bees are raised and an economically important disease in many honey-producing countries. Infected larvae usually die rapidly when they are 3-5 days old and in severe cases entire colonies can be lost.
Subject: NC_012633:276500 Rickettsia africae ESF-5, complete genome
Lineage: Rickettsia africae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This organism was isolated from a cattle tick, Amblyomma variegatum, collected in Ethiopia. This organism, a member of the spotted fever group of the Rickettsiales, is found in sub-Saharan Africa and the Caribbean. Rickettsia africae causes a flu-like illness, characterized by a mild fever and severe headache, without the skin rash common to other spotted fever group Rickettsia species. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms.