Query: NC_016931:269537 Rickettsia massiliae str. AZT80 chromosome, complete genome Lineage: Rickettsia massiliae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This bacterium is a member of the spotted fever group of the Rickettsiales and has been isolated from ticks in Europe and Africa. Rickettsia massiliae does not appear to cause disease in humans.
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General Information: An endosymbiont of free-living amoebae (Acanthamoeba sp. endosymbiont UWE25) and implicated as a potential human pathogen this strain is an environmental isolate. Amoeba endosymbiont. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. Candidatus Protochlamydia amoebophila, originally Parachlamydia is an endosymbiont of free-living amoebae (Acanthamoeba). This organism is an obligate intracellular endosymbiont and lives in small inclusions dispersed throughout the host cell.