Pre_GI: SWBIT SVG BLASTP

Query: NC_016931:171444 Rickettsia massiliae str. AZT80 chromosome, complete genome

Lineage: Rickettsia massiliae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This bacterium is a member of the spotted fever group of the Rickettsiales and has been isolated from ticks in Europe and Africa. Rickettsia massiliae does not appear to cause disease in humans.

Subject: NC_007798:586500 Neorickettsia sennetsu str. Miyayama, complete genome

Lineage: Neorickettsia sennetsu; Neorickettsia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This organism was first described in 1953 in Japan as causing Sennetsu fever. Causes an infectious mononucleosis-like disease. Like other Ehrlichia, this organism is an obligate intracellular pathogen. It can be transmitted from fish flukes (trematodes) to humans, and was one of the first Ehrlichia that was found to cause a human-specific illness.