Query: NC_016930:943000 Rickettsia philipii str. 364D chromosome, complete genome
Lineage: Rickettsia philipii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Rickettsiae are obligate intracellular Gram-negative bacteria mostly found in arthropods, some of which cause mild to severe diseases in humans. Spotted fever group rickettsiae (SFGR) cause disease in humans. R .philippi strain 364D, an SFGR, was isolated in 1966 from Dermacentor occidentalis ticks collected in Ventura county, California, and since then 364D has been detected in up to 11% of D. occidentalis from 8 California counties. It has now been recognized as causing eschar-associated illness.
Subject: NC_012225:2421783 Brachyspira hyodysenteriae WA1, complete genome
Lineage: Brachyspira hyodysenteriae; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria
General Information: Brachyspira hyodysenteriae is the causative agent of swine dysentery, which is a severe mucohemorrhagic diarrheal disease of pigs that has economic significance for pork-producing countries. The bacterium can survive for several weeks in cold moist conditions but not under warm dry conditions. It spreads slowly, building up in numbers as the dose rate of the causal agent builds up in the environment. Pigs that recover develop a low immunity and rarely suffer from the disease again. It can be spread by other organisms (flies, mice, birds and dogs) or external mechanical factors; its main habitat is the porcine cecum and colon. It is chemotactically attracted to mucin which it penetrates with a corkscrew-like motility.