Pre_GI: SWBIT SVG BLASTP

Query: NC_016930:943000 Rickettsia philipii str. 364D chromosome, complete genome

Lineage: Rickettsia philipii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Rickettsiae are obligate intracellular Gram-negative bacteria mostly found in arthropods, some of which cause mild to severe diseases in humans. Spotted fever group rickettsiae (SFGR) cause disease in humans. R .philippi strain 364D, an SFGR, was isolated in 1966 from Dermacentor occidentalis ticks collected in Ventura county, California, and since then 364D has been detected in up to 11% of D. occidentalis from 8 California counties. It has now been recognized as causing eschar-associated illness.

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Subject: NC_006833:409599 Wolbachia endosymbiont strain TRS of Brugia malayi, complete

Lineage: Wolbachia endosymbiont of Brugia malayi; Wolbachia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: A nematode endosymbiont. This group of bacteria are associated with a variety of invertebrate species, some as pathogens, some in a symbiotic relationship. Typically these organisms are transmitted maternally from mother to daughter transovarially (through the egg) although these bacteria can affect their hosts reproductive capabilities in order to enhance transmission. The net outcome is the increase of hosts carrying the bacteria in the next generation, thereby increasing transmission. This strain naturally infects Brugia malayi, a parasitic filarial nematode that causes lymphatic filariasis, one of the most devastating diseases in humans. The endosymbiont plays important roles in the biology of the nematide host. One of the known such effects are aberrant sex ratios in the host, parthenogenesis and feminization of genetic males, etc.