Query: NC_016929:197403 Rickettsia canadensis str. CA410 chromosome, complete genome
Lineage: Rickettsia canadensis; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was originally thought to be a member of the typhus group of Rickettsiales, however, it is now thought to represent a distict group with the rickettsia.
Subject: NC_012225:236490 Brachyspira hyodysenteriae WA1, complete genome
Lineage: Brachyspira hyodysenteriae; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria
General Information: Brachyspira hyodysenteriae is the causative agent of swine dysentery, which is a severe mucohemorrhagic diarrheal disease of pigs that has economic significance for pork-producing countries. The bacterium can survive for several weeks in cold moist conditions but not under warm dry conditions. It spreads slowly, building up in numbers as the dose rate of the causal agent builds up in the environment. Pigs that recover develop a low immunity and rarely suffer from the disease again. It can be spread by other organisms (flies, mice, birds and dogs) or external mechanical factors; its main habitat is the porcine cecum and colon. It is chemotactically attracted to mucin which it penetrates with a corkscrew-like motility.