Query: NC_016894:77853 Acetobacterium woodii DSM 1030 chromosome, complete genome Lineage: Acetobacterium woodii; Acetobacterium; Eubacteriaceae; Clostridiales; Firmicutes; Bacteria General Information: Acetobacterium woodii is a Gram positive, motile, strict anaerobic, acetogenic bacterium, that relies on Na+ as coupling ion in bioenergetic reactions. The organism can use a wide range of substrates, such as sugars, alcohols, methoxylated aromatic acids or C1 compounds. Electrons derived from these electron donors are used in the Wood-Ljungdahl-pathway where the organism fixes CO2 and produces acetate. The pathway of CO2-fixation is coupled to energy conservation via a chemiosmotic mechanism, one enzyme that seems to be involved is the Rnf complex. The produced Na+ gradient can be used to drive ATP-synthesis or flagella rotation. The ATP synthase is a member of the F1FO class of enzymes and has an unusual hybrid rotor. Can use alternative electron acceptors like the lignin degradation product caffeate.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This strain (81-176; Penner serotype 23/36) was isolated during an outbreak of campylobacteriosis in Minnesota, USA, due to the consumption of contaminated milk. This organism is the leading cause of bacterial food poisoning (campylobacteriosis) in the world, and is more prevalent than Salmonella enteritis (salmonellosis). Found throughout nature, it can colonize the intestines of both mammals and birds, and transmission to humans occurs via contaminated food products. This organism can invade the epithelial layer by first attaching to epithelial cells, then penetrating through them. Systemic infections can also occur causing more severe illnesses.