Query: NC_016887:221788 Nocardia cyriacigeorgica GUH-2, complete genome Lineage: Nocardia cyriacigeorgica; Nocardia; Nocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Isolated from a fatal human nocardiosis case at Washington DC, USA in the 1970s. Human pathogen. Nocardia cyriacigeorgica is a filamentous actinobacteria, frequently isolated from diseased human and animal tissues. N. cyriacigeorgica is the most prevalent species responsible for nocardiosis in North America, while placing fourth in France.
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General Information: Isolated in 1960 in Turkey. Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. This organism is similar to B. pseudomallei and is differentiated by being nonmotile. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.