Pre_GI: SWBIT SVG BLASTP

Query: NC_016843:747950 Treponema pallidum subsp. pertenue str. Gauthier chromosome,

Lineage: Treponema pallidum; Treponema; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated in Brazzaville, the Republic of Congo in 1960. Treponema pallidum subsp. pertenue causes chronic and disfiguring illness called yaws. The disease starts as a skin infection causing persistent ulcers and progresses to form tumor-like masses. This disease tends to infect children and is common in rural areas in Africa, Southeast Asia and equatorial South America.

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BLASTP Alignment.txt

Subject: NC_008245:1625715 Francisella tularensis subsp. tularensis FSC 198, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, the strain FSC 198 was isolated in Slovakia from a mite and is virulent in an animal model. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.