Pre_GI: SWBIT SVG BLASTP

Query: NC_016789:199503 Corynebacterium diphtheriae PW8 chromosome, complete genome

Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs.

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BLASTP Alignment.txt

Subject: NC_007164:1839154 Corynebacterium jeikeium K411, complete genome

Lineage: Corynebacterium jeikeium; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from the axilla of a bone marrow transplant patient. A serious nocosomial pathogen. This bacterium is a lipophilic and multidrug resistant member of the human skin flora. This species has been associated with bacterial endocarditis following cardiac surgery. Other nocosomial infections involving this organism are associated with immunocompromised patients with malignancies, in-place medical devices, breaks in the skin barrier, and therapy with broad-spectrum antibiotics.