Pre_GI: SWBIT SVG BLASTP

Query: NC_016788:655175 Corynebacterium diphtheriae HC04 chromosome, complete genome

Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs.

Subject: NC_015760:8914 Streptococcus salivarius CCHSS3, complete genome

Lineage: Streptococcus salivarius; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: The commensal bacterium Streptococcus salivarius is predominant specie of the human oropharyngeal tract and exerts an important role in oral ecology. Streptococcus salivarius is an aerobic, gram-positive coccus. This organism is the most common organism isolated from the human oral cavity. Streptococcus salivarius can also be an opportunistic pathogen causing endocarditis, blood infection, and peritonitis. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes.