Query: NC_016788:655175 Corynebacterium diphtheriae HC04 chromosome, complete genome Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria General Information: They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs.
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General Information: This bacterium can grow using carbon monoxide as the sole carbon and energy source and the cells contain a well characterized nitrogenase system that is post-translationally modified by ADP-ribosylation. Phototrophic bacterium. This organism is an anoxygenic phototrophic bacterium that does not produce oxygen, but instead produces extracellular elemental sulfur when harvesting light energy. The bacterium lacks the light harvesting complex 2 (LHC2) normally found in photosynthetic bacteria meaning it contains one of the simplest photosynthetic systems studied.