Query: NC_016779:4039103 Bacillus cereus F837/76 chromosome, complete genome
Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria
General Information: This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.
Subject: NC_011134:1222739 Streptococcus equi subsp. zooepidemicus str. MGCS10565, complete
Lineage: Streptococcus equi; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: Streptococcus equi subsp. zooepidemicus str. MGCS10565 was responsible for a large and severe epidemic outbreak of poststreptococcal glomerulonephritis. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. Streptococcus equi is comprised of three subspecies equi, zooepidemicus and ruminatorum all of which cause disease in horses, sheep or goats. Streptococcus equi subsp. zooepidemicus has also been isolated from clinical cases in humans and other animals. This species is a Lancefield C group bacterium.