Query: NC_016745:3170384 Oceanimonas sp. GK1 chromosome, complete genome
Lineage: Oceanimonas; Oceanimonas; Aeromonadaceae; Aeromonadales; Proteobacteria; Bacteria
General Information: Oceanimonas sp. (strain GK1) is an aerobic, marine halotolerant, Gram-negative bacterium isolated from Gavkhouni Wetland in Iran. It is a motile bacterium which can tolerate up to 12% NaCl. It grows at tempatures between 10 to 45 degrees C with an optimum at 35 degrees C and at pH between 6 to 10 with an optimum at 8. Oceanimonas sp. produces large amounts of poly-hydroxybutyrate (PHB) as a carbon and energy reservoir under unbalanced growth conditions. PHB is a biodegradable and renewable biosynthetic polymer which can be used in medicine, tissue engineering, and packaging materials.
Subject: NC_009648:4958500 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome
Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.