Query: NC_016612:5600177 Klebsiella oxytoca KCTC 1686 chromosome, complete genome
Lineage: Klebsiella oxytoca; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This bacterium can cause spontaneous infectious spondylodiscitis (SIS), an uncommon cause of low back pain in adults, but most commonly described in children. This species can be differentiated from Klebsiella pneumoniae by its inability to produce indole from tryptophan.
Subject: NC_010742:1794000 Brucella abortus S19 chromosome 1, complete sequence
Lineage: Brucella abortus; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta by Dr. David Bruce during an epidemic among British soldiers. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.