Query: NC_016610:726128 Tannerella forsythia ATCC 43037 chromosome, complete genome Lineage: Tannerella forsythia; Tannerella; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria General Information: This organism is a key agent in the progression of periodontal disease and is involved in bone loss and loss of attachment of teeth. The pathogenic factors involved in this are poorly understood. Unlike other periodontal organism such as Porphyromonas gingivalis and Prevotella intermedia, this organism is difficult to culture and the prevalence of the organism in periodontal disease may be underestimated. This organism is synergistic with Porphyromonas gingivalis, and the presence of both accelerates progression of the disease.
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General Information: This strain differs from other isolates based on the combination of its ability to use 2,5-dichlorophenol and its inability to use nitrate as a strong electron acceptor. It can also dechlorinate 2,4-dichlorophenol and 2,4,6-trichlorophenol much faster than other isolates. Can dehalogenate chlorinated phenols. This anaerobic species was originally isolated by enrichment and isolation of single plate-grown colonies, and was the first pure culture of myxobacteria able to grow anaerobically.