Pre_GI: SWBIT SVG BLASTP

Query: NC_016610:3297080 Tannerella forsythia ATCC 43037 chromosome, complete genome

Lineage: Tannerella forsythia; Tannerella; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is a key agent in the progression of periodontal disease and is involved in bone loss and loss of attachment of teeth. The pathogenic factors involved in this are poorly understood. Unlike other periodontal organism such as Porphyromonas gingivalis and Prevotella intermedia, this organism is difficult to culture and the prevalence of the organism in periodontal disease may be underestimated. This organism is synergistic with Porphyromonas gingivalis, and the presence of both accelerates progression of the disease.

Subject: NC_018664:985689 Clostridium acidurici 9a chromosome, complete genome

Lineage: Gottschalkia acidurici; Gottschalkia; ; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium acidiurici is an obligate anaerobic Gram-positive bacterium that is motile and spore-forming. It can be isolated from almost every soil but can also be found in the intestinal tract of birds. It is able to use purines like uric acid as sole carbon, nitrogen and energy source to build ammonia, carbon dioxide and acetic acid. Unlike most other Clostridia it is a specialist and not able to grow on sugars or different other substrates than purines.