Pre_GI: SWBIT SVG BLASTP

Query: NC_016605:1177485 Pediococcus claussenii ATCC BAA-344 chromosome, complete genome

Lineage: Pediococcus claussenii; Pediococcus; Lactobacillaceae; Lactobacillales; Firmicutes; Bacteria

General Information: Pediococci are lactic acid bacteria found on plants and in many fermented foods. Pediococcus claussenii is a brewery contaminant that can cause economic loss in the brewing industry.

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Subject: NC_006142:243899 Rickettsia typhi str. Wilmington, complete genome

Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.