Pre_GI: SWBIT SVG BLASTP

Query: NC_016584:593954 Desulfosporosinus orientis DSM 765 chromosome, complete genome

Lineage: Desulfosporosinus orientis; Desulfosporosinus; Peptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Country: Singapore; Isolation: Soil at pumping station; Temp: Mesophile; Temp: 30C. The genus Desulfotomaculum, which means a sausage (shaped organism) that reduces sulfur compounds, was first described in 1965. Desulfosporosinus orientis is a strictly anaerobic, chemoorganotrophic, Gram-positive bacterium.

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BLASTP Alignment.txt

Subject: NC_010263:278463 Rickettsia rickettsii str. Iowa, complete genome

Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.