Query: NC_016584:593954 Desulfosporosinus orientis DSM 765 chromosome, complete genome Lineage: Desulfosporosinus orientis; Desulfosporosinus; Peptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: Country: Singapore; Isolation: Soil at pumping station; Temp: Mesophile; Temp: 30C. The genus Desulfotomaculum, which means a sausage (shaped organism) that reduces sulfur compounds, was first described in 1965. Desulfosporosinus orientis is a strictly anaerobic, chemoorganotrophic, Gram-positive bacterium.
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General Information: This strain (UTI89) is a uropathogenic strain isolated from a woman with uncomplicated cystitis (bladder inflammation) that has been demonstrated to cause cystitis in a murine urinary tract infection model. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.