Query: NC_016514:3048883 Enterobacter cloacae EcWSU1 chromosome, complete genome
Lineage: Enterobacter cloacae; Enterobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: These "ICU bugs" cause significant morbidity and mortality, and infection management is complicated by multiple antibiotic resistance. These bacteria possess inducible beta-lactamases, which are undetectable in vitro but are also responsible for resistance during treatment
Subject: NC_009079:402891 Burkholderia mallei NCTC 10247 chromosome I, complete sequence
Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: Isolated in 1960 in Turkey. Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. This organism is similar to B. pseudomallei and is differentiated by being nonmotile. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.