Query: NC_016514:3048883 Enterobacter cloacae EcWSU1 chromosome, complete genome
Lineage: Enterobacter cloacae; Enterobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: These "ICU bugs" cause significant morbidity and mortality, and infection management is complicated by multiple antibiotic resistance. These bacteria possess inducible beta-lactamases, which are undetectable in vitro but are also responsible for resistance during treatment
Subject: NC_006349:400807 Burkholderia mallei ATCC 23344 chromosome 2, complete sequence
Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: This type strain came from a Chinese patient in Burma who had glanders in 1944. Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.