Query: NC_016510:2426150 Flavobacterium columnare ATCC 49512 chromosome, complete genome Lineage: Flavobacterium columnare; Flavobacterium; Flavobacteriaceae; Flavobacteriales; Bacteroidetes; Bacteria General Information: Isolated in 1987 from a skin lesion of a brown trout fry in France. Fish pathogen. Purified genomic DNA obtained from ATCC 49512 F. columnare is considered ubiquitous in the warmwater aquatic environment, and it is the causative agent of columnaris disease in fish. Columnaris disease is common throughout the world and infects most species of freshwater fish, including aquaculture species, wild fish populations, and ornamental fish.
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General Information: This serovar has a narrow host range and causes a typhoid-like (paratyphoid fever) illness in humans. It is especially prevalent in southern and eastern Asia, and has been associated with some particularly virulent outbreaks. A number of isolates are increasingly antibiotic resistant. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.