Query: NC_016445:2663837 Vibrio cholerae O1 str. 2010EL-1786 chromosome 1, complete Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria General Information: This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae O1 str. 2010EL-1786 (ATCC BAA-2163) is a 2010 outbreak strain of Vibrio cholerae from Haiti. Isolated from stool sample from patient with cholera.
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General Information: This strain (SGSC 4150; ATCC BAA-1250) was isolated from a stool sample of an infected woman in Penang, Malaysia, May 16, 2002. This strain is susceptible to antibiotics, and was classified as serovar Paratyphi B because it was unable to metabolize D-tartrate. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.