Query: NC_016148:463840 Thermovirga lienii DSM 17291 chromosome, complete genome Lineage: Thermovirga lienii; Thermovirga; Synergistaceae; Synergistales; Synergistetes; Bacteria General Information: Country: Norway; Environment: Oil fields, Fresh water; Isolation: Production water from an oil well, Norway; Temp: Thermophile; Temp: 58C. Thermovirga lienii was isolated from an oil well in the North Sea.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This strain (live vaccine strain) was created in the 1960's in the USA and provides protection against tularemia in animal models as well as in humans. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.