Query: NC_016114:4922630 Streptomyces flavogriseus ATCC 33331 chromosome, complete genome Lineage: Streptomyces pratensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Environment: Soil; Isolation: Soil; Temp: Mesophile. The genus Streptomyces consists of soil and water Gram positive filamentous bacteria well known for their ability to produce complex secondary metabolites including many antibiotics. Additionally they undergo complex multicellular development, with spores germinating to form a branched, multinucleoid substrate mycelium, which then produces an aerial mycelium which septates into uninucleoid spores. Streptomyces flavogriseus is an aerobic, Gram-positive bacterium isolated from soil. This organism produces cellulases and xyanases that are able to degrade cellulose and xylan.
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General Information: This organism is the causative agent of scrub typhus, and like other members of the Rickettsiales is an obligate intracellular organism. Scrub typhus, which occurs in rural and agricultural areas, is one of the most common infectious diseases in southeast Asia where an estimated 1 million cases occur each year. Many cases are mild, but if left untreated, a variety of serious illnesses can arise and fatality rates can range from 1-35%. Transmission occurs via an insect vector through the bite of the larval trombiculid mite (chiggers). The bacterium is transmitted transovarially in mites (from females to their offspring).