Query: NC_016111:3769818 Streptomyces cattleya NRRL 8057, complete genome
Lineage: Streptomyces cattleya; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Streptomyces cattleya, a producer of the antibiotics thienamycin and cephamycin C, is one of the rare bacteria known to synthesize fluorinated metabolites. Gram-positive bacterium originally isolated from soil. The bacterium Streptomyces cattleya has become an organism of interest due to its ability to produce various antibiotics (thienamycin, cephamycin C, penicillin N) and to excrete the fluorinated antibiotic 4-fluorothreonine when cultivated in the presence of fluorine.
Subject: NC_009012:3204696 Clostridium thermocellum ATCC 27405, complete genome
Lineage: Clostridium thermocellum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria
General Information: This strain is a well studied producer of endoglucanase and several restriction endonucleases. Thermophilic cellulose degrading bacterium. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a thermophilic anaerobe that produces an extracellular enzyme system capable of degrading crystalline cellulose to soluble sugars that are further utilized as the carbon source for growth.