Query: NC_016111:3486000 Streptomyces cattleya NRRL 8057, complete genome
Lineage: Streptomyces cattleya; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Streptomyces cattleya, a producer of the antibiotics thienamycin and cephamycin C, is one of the rare bacteria known to synthesize fluorinated metabolites. Gram-positive bacterium originally isolated from soil. The bacterium Streptomyces cattleya has become an organism of interest due to its ability to produce various antibiotics (thienamycin, cephamycin C, penicillin N) and to excrete the fluorinated antibiotic 4-fluorothreonine when cultivated in the presence of fluorine.
Subject: NC_014121:3776902 Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete
Lineage: Enterobacter cloacae; Enterobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: Enterobacter species are found in natural environments such as water, sewage, soil, and vegetables; some species are found in human and animal species. Enterobacter cloacae is a prevalent nosocomial pathogen as it is highly resistant to disinfectants and antimicrobial agents. E.cloacae subsp. cloacae strain ATCC 13047 was isolated from human cerebrospinal fluid in 1890 and is the type strain. These "ICU bugs" cause significant morbidity and mortality, and infection management is complicated by multiple antibiotic resistance. These bacteria possess inducible beta-lactamases, which are undetectable in vitro but are also responsible for resistance during treatment.