Query: NC_016077:388941 Acidaminococcus intestini RyC-MR95 chromosome, complete genome
Lineage: Acidaminococcus intestini; Acidaminococcus; Acidaminococcaceae; Selenomonadales; Firmicutes; Bacteria
General Information: The organisms of the genus Acidaminococcus are normal members of microbiota of human and warm-blooded animals, and are occasionally involved in opportunistic human infections
Subject: NC_008343:2020785 Granulibacter bethesdensis CGDNIH1, complete genome
Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.