Pre_GI: SWBIT SVG BLASTP

Query: NC_016050:938000 Rickettsia japonica YH, complete genome

Lineage: Rickettsia japonica; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: The causal agent of Oriental Spotted Fever. Human pathogen. Rickettsiae are obligate intracellular Gram-negative bacteria mostly found in arthropods, some of which cause mild to severe diseases in humans. Rickettsia japonica strain YH was isolated in 1985 from the blood of a patient with febrile exanthematous illness in Japan.

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BLASTP Alignment.txt

Subject: NC_003210:2721559 Listeria monocytogenes EGD-e, complete genome

Lineage: Listeria monocytogenes; Listeria; Listeriaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain has numerous pathogenicity islands and genes as compared to the related non-pathogenic organism Listeria innocua. This organism, which causes listeriosis, is one of the leading causes of death from food-borne pathogens especially in pregnant women, newborns, the elderly, and immunocompromised individuals. It is found in environments such as decaying vegetable matter, sewage, water, and soil, and it can survive extremes of both temperatures (1-45 degrees C) and salt concentration marking it as an extremely dangerous food-born pathogen, especially on food that is not reheated. This organism is enteroinvasive, and utilizes an actin-based motility system by using a surface protein, ActA, that promotes actin polymerization, to spread intercellularly using the polymerized cytoskeletal protein as a "motor". There are 13 serovars associated with Listeria monocytogenes, and the serovar 4b strains are more commonly associated with invasive disease.