Query: NC_016050:938000 Rickettsia japonica YH, complete genome Lineage: Rickettsia japonica; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: The causal agent of Oriental Spotted Fever. Human pathogen. Rickettsiae are obligate intracellular Gram-negative bacteria mostly found in arthropods, some of which cause mild to severe diseases in humans. Rickettsia japonica strain YH was isolated in 1985 from the blood of a patient with febrile exanthematous illness in Japan.
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General Information: This strain is a methicillin-resistant (MRSA) strain with vancomycin resistance (VRSA) isolated in 1997 from the pus of a Japanese male baby with a surgical wound infection that did not respond to vancomycin. Causes skin infections. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. S. aureus continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.