Query: NC_016023:1725294 Bacillus coagulans 36D1 chromosome, complete genome Lineage: Bacillus coagulans; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Bacillus coagulans, a lactic acid producing bacterium, was first identified as a spoilage agent of milk products. This organism can be used in the production of ethanol and lactic acid from cellulose and hemicellulose acid hydrolysate. Bacillus coagulans also produces other commercially important chemicals like cyclodextrins and amylases, and has been used as a probiotic in animal feed.
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General Information: Thermomicrobium roseum DSM 5159 was isolated from Yellowstone National Park, USA. Obligate thermophile with unusual cell wall structure. Thermomicrobium roseum is a red-pigmented, rod-shaped, Gram-negative extreme thermophile that possesses both an atypical cell wall composition and an unusual cell membrane that is composed entirely of long-chain 1,2-diols. Analyses of environmental sequences from hot spring environments show that T.roseum displays a low quantity but ubiquitous presence in top layers of microbial mats. Few standard housekeeping genes are found on the megaplasmid, however, it does encode a complete system for chemotaxis including both chemosensory components and an entire flagellar apparatus. T. roseum oxidizes CO aerobically, making it the first thermophile known to do so. In addition, is is propose that glycosylation of its carotenoids plays a crucial role in the adaptation of the cell membrane to this bacterium's thermophilic lifestyle. Because T. roseum is a deep-branching member of this phylum, eventhough this species is not photosynthetic, analysis of the genome provides some insight into the origins of photosynthesis in the Chloroflexi.