Query: NC_016023:1725294 Bacillus coagulans 36D1 chromosome, complete genome Lineage: Bacillus coagulans; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Bacillus coagulans, a lactic acid producing bacterium, was first identified as a spoilage agent of milk products. This organism can be used in the production of ethanol and lactic acid from cellulose and hemicellulose acid hydrolysate. Bacillus coagulans also produces other commercially important chemicals like cyclodextrins and amylases, and has been used as a probiotic in animal feed.
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General Information: This strain (originally 5636/77) was isolated from a diarrheic patient in 1977 and minimally passaged. This organism is the leading cause of bacterial food poisoning (campylobacteriosis) in the world, and is more prevalent than Salmonella enteritis (salmonellosis). Found throughout nature, it can colonize the intestines of both mammals and birds, and transmission to humans occurs via contaminated food products. This organism can invade the epithelial layer by first attaching to epithelial cells, then penetrating through them. Systemic infections can also occur causing more severe illnesses.