Query: NC_015949:1180755 Caldicellulosiruptor lactoaceticus 6A chromosome, complete genome Lineage: Caldicellulosiruptor lactoaceticus; Caldicellulosiruptor; Thermoanaerobacterales Family III; Thermoanaerobacterales; Firmicutes; Bacteria General Information: Environment: Hot spring; Isolation: Alkaline hot spring; Iceland, Hveragerdi; Temp: Thermophile; Temp: 79C; Caldicellulosiruptor lactoaceticus is an extreme thermophile spore-forming bacterium. This organism produces a thermostable cellulase which may have industrial uses.
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General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.