Query: NC_015943:1 Haloarcula hispanica ATCC 33960 chromosome chromosome II, complete Lineage: Haloarcula hispanica; Haloarcula; Halobacteriaceae; Halobacteriales; Euryarchaeota; Archaea General Information: Haloarcula hispanica is a halophilic archaeon. Extremely halophilic archaeon. Has an unusually low restriction barrier. First isolated from a solar saltern in Spain. Ability to accumulate polyhydroxyalkanoate (PHA) when carbon sources are in excess.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.