Query: NC_015921:481532 Borrelia bissettii DN127 chromosome, complete genome Lineage: Borrelia bissettii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria General Information: Borrelia bissettii DN127 was isolated from a western blackleg tick, Ixodes pacificus, in California. This strain has pattern of outer surface proteins that is different from many other North American strains. Human pathogen.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.