Query: NC_015722:462450 Candidatus Midichloria mitochondrii IricVA chromosome, complete
Lineage: Midichloria mitochondrii; Midichloria; Candidatus Midichloriaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Candidatus Midichloria mitochondrii is a symbiont of the tick Ixodes ricinus. The importance of this organism is two-fold. this symbiont is the only bacterium described that is able of invading the mitochondria of animals. The host Ixodes ricinus is a vector of a number of human diseases.
Subject: NC_007799:968499 Ehrlichia chaffeensis str. Arkansas, complete genome
Lineage: Ehrlichia chaffeensis; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.