Query: NC_015713:2453409 Simkania negevensis Z chromosome gsn.131, complete genome Lineage: Simkania negevensis; Simkania; Simkaniaceae; Chlamydiales; Chlamydiae; Bacteria General Information: This bacterium is named after Simona Kahane who discovered the organism as a contaminant in cell cultures at Ber Sheva, in the Negev Desert, Israel, in 1993. Simkania negevensis is a member of the order Chlamydiales and can reside intracellularly and has a slow prolonged developmental cycle. It has a wide geographical and environmental distribution and is associated with pneumonia, bronchiolitis and chronic obstructive pulmonary disease, furthermore, it is completely resistant to penicillin and to bacitracin. The natural hosts of Simkania negevensis bacteria might be amoebae.
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General Information: Environment: Rhizosphere, Host, Rhizosphere-colonizing; Temp: Mesophile. This species is an uncommon but serious source of infection in patients with breathing tubes such as endotracheal or tracheostomy tubes, or with chronically indwelling urinary catheters. Although the organism can colonize the devices without causing an infection, under certain conditions it can cause pneumonia, urinary tract infections, or an infection of the blood. This organism can also cause infection in immunocompromised patients. It has resistance to many commonly used antibiotics and therefore is often difficult to eradicate. Most strains are resistant to co-trimoxazole.