Query: NC_015703:1992000 Runella slithyformis DSM 19594 chromosome, complete genome Lineage: Runella slithyformis; Runella; Cytophagaceae; Cytophagales; Bacteroidetes; Bacteria General Information: Environment: Fresh water, Host; Isolation: Fresh water lake; USA, Louisiana, Baton; Temp: Psychrophile. This is a species of curved, nonflexible, pink bacteria. The species is of interest because it is able to grow at temperatures as low as 4°C. The species epithet is derived from slithy, a nonsense word from Lewis Carroll's Jabberwocky for a fictional organism that is 'slithy' and the Latin word 'suffix' meaning '-like, in the shape of', yielding the Neo-Latin word 'slithyformis' meaning 'slithy in form'.
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General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.