Query: NC_015690:7422911 Paenibacillus mucilaginosus KNP414 chromosome, complete genome Lineage: Paenibacillus mucilaginosus; Paenibacillus; Paenibacillaceae; Bacillales; Firmicutes; Bacteria General Information: Paenibacillus mucilaginosus is critical silicate bacteria in the biogeochemical cycling of potassium, phosphorus, and other soil elements, and is widely used in agriculture, bioleaching, and wastewater treatment. P. mucilaginosus is able to degrade insoluble soil minerals with the release of nutritional ions and fix nitrogen, and thus it has been successfully used as a biofertilizer since the 1990s. The exocellular polysaccharides produced by P. mucilaginosus is also an effective bioflocculant, and thus plays a potential role in the treatment of wastewater and biohydrometallurgy.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.