Query: NC_015687:155554 Clostridium acetobutylicum DSM 1731 chromosome, complete genome
Lineage: Clostridium acetobutylicum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria
General Information: This organism is a benign saccharolytic and proteolytic soil bacterium capable of producing a number of organic solvents (solventogenic bacterium) through fermentation of various organic compounds. The first strains of C. acetobutyricum were isolated by Chaim Weizman during the World War I and used to develop industrial starch-based acetone, butanol and ethanol fermentation processes.
Subject: NC_007618:1792500 Brucella melitensis biovar Abortus 2308 chromosome I, complete
Lineage: Brucella abortus; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: This strain is a standard laboratory strain. It is virulent for humans and cattle. Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.