Query: NC_015672:2102580 Flexistipes sinusarabici DSM 4947 chromosome, complete genome Lineage: Flexistipes sinusarabici; Flexistipes; Deferribacteraceae; Deferribacterales; Deferribacteres; Bacteria General Information: Country: Red Sea; Environment: Marine; Isolation: Brine water; Atlantis II Deep, Red Sea; Temp: Thermophile; Temp: 45 - 50C. This is a gram-negative flexible bacterium isolated from brine water samples of the Atlantis II Deep of the Red Sea at a depth of 2000 m. Halophilic and moderately thermophilic.
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General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.