Query: NC_015581:128350 Thioalkalimicrobium cyclicum ALM1 chromosome, complete genome Lineage: Thioalkalimicrobium cyclicum; Thioalkalimicrobium; Piscirickettsiaceae; Thiotrichales; Proteobacteria; Bacteria General Information: Isolation: Water; USA, California, Lake Mono. This organism is a sulfur-oxidizing bacterium isolated from highly alkaline soda lakes. These bacteria have a pH optimum of 10 and are able to oxidize sulfide, thiosulfate and tetrathionate.
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General Information: This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Myxococcus fulvus produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.