Query: NC_015581:771482 Thioalkalimicrobium cyclicum ALM1 chromosome, complete genome
Lineage: Thioalkalimicrobium cyclicum; Thioalkalimicrobium; Piscirickettsiaceae; Thiotrichales; Proteobacteria; Bacteria
General Information: Isolation: Water; USA, California, Lake Mono. This organism is a sulfur-oxidizing bacterium isolated from highly alkaline soda lakes. These bacteria have a pH optimum of 10 and are able to oxidize sulfide, thiosulfate and tetrathionate.
Subject: NC_008343:823093 Granulibacter bethesdensis CGDNIH1, complete genome
Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.