Pre_GI: SWBIT SVG BLASTP

Query: NC_015581:128350 Thioalkalimicrobium cyclicum ALM1 chromosome, complete genome

Lineage: Thioalkalimicrobium cyclicum; Thioalkalimicrobium; Piscirickettsiaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: Isolation: Water; USA, California, Lake Mono. This organism is a sulfur-oxidizing bacterium isolated from highly alkaline soda lakes. These bacteria have a pH optimum of 10 and are able to oxidize sulfide, thiosulfate and tetrathionate.

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Subject: NC_012633:169444 Rickettsia africae ESF-5, complete genome

Lineage: Rickettsia africae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This organism was isolated from a cattle tick, Amblyomma variegatum, collected in Ethiopia. This organism, a member of the spotted fever group of the Rickettsiales, is found in sub-Saharan Africa and the Caribbean. Rickettsia africae causes a flu-like illness, characterized by a mild fever and severe headache, without the skin rash common to other spotted fever group Rickettsia species. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms.