Query: NC_015474:644552 Pyrococcus sp. NA2 chromosome, complete genome
Lineage: Pyrococcus; Pyrococcus; Thermococcaceae; Thermococcales; Euryarchaeota; Archaea
General Information: Pyrococcus has similar characteristics of other thermoautotrophican archaea such as Archaeoglobus, and Methanococcus in the respect that they are all thermophilic and anaerobic. Pyrococcus differs, however, because its optimal growth temperature is nearly 100 °C and dwells at a greater sea depth than the other archaea. Studying Pyrococcus helps give insight to possible mechanisms used to endure extreme environmental conditions like high temperatures and high pressure.
Subject: NC_007354:1087456 Ehrlichia canis str. Jake, complete genome
Lineage: Ehrlichia canis; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.