Query: NC_015186:2197236 Acidiphilium multivorum AIU301, complete genome Lineage: Acidiphilium multivorum; Acidiphilium; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Thiosulfate oxidation. Acidophilic, aerobic, anoxygenic, phototrophic, Gram-negative bacterium isolated from pyritic acid mine drainage. A.multivorum has high ability of resistance to various metals under acidic condition, and require high acidity for growth. It exhibits tolerance towards some heavy metal ions like nickel, zinc, cadmium and copper, and resistance to arsenate and arsenite.
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General Information: This organism is the causative agent of Glasser's disease in swine but is usually found as a commensal organism in the upper respiratory tract. Glasser's disease is responsible for significant losses in swine husbandry. The disease was first noted in 1910 by Glasser and the organism requires factor V (NAD - nicotinamide adenine dinucleotide) growth factor, like H. suis, but not factor X (iron porphyrin) which H. suis requires. Pathogenicity and virulence are often strain specific. Symptoms include fibrinous polyserositis (fibrous inflammation of serous membranes, polyarthritis (inflammation of multiple joints) and meningitis (inflammation of meninges)and pneumonia.