Pre_GI: SWBIT SVG BLASTP

Query: NC_015067:2282000 Bifidobacterium longum subsp. longum JCM 1217, complete genome

Lineage: Bifidobacterium longum; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria

General Information: This organism is found in adult humans and formula fed infants as a normal component of gut flora. Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity.

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BLASTP Alignment.txt

Subject: NC_021182:1 Clostridium pasteurianum BC1, complete genome

Lineage: Clostridium pasteurianum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Environment: Soil; Isolation: Coal-cleaning residues; Temp: Mesophile; Temp: 30C. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. Clostridium pasteurianum was first isolated from soil by the Russian microbiologist Sergey Winogradsky. This organism is able to fix nitrogen and oxidize hydrogen into protons. The genes involved in nitrogen fixation and hydrogen oxidation have been extensively studied in this organism.