Query: NC_014964:557910 Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, complete Lineage: Thermoanaerobacter brockii; Thermoanaerobacter; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria General Information: Isolation: Lake sediment; Africa, Lake Kivu; Temp: Thermophile; Temp: 65C. Thermoanaerobacter brockii is a thermophilic gram positive anaerobe that has been isolated from lake sediment, oil wells and hot springs. This organism ferments hexoses and pyruvate and can reduce thiosulfate to hydrogen sulfide.
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General Information: This subspecies is virulent in humans, the strain FSC 198 was isolated in Slovakia from a mite and is virulent in an animal model. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.