Query: NC_014921:313312 Mycoplasma fermentans M64 chromosome, complete genome Lineage: Mycoplasma fermentans; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria General Information: Mycoplasma fermentans has been isolated from the respiratory and urogenital tract, primarily from immunocompromised patients and may be a factor in the progression of HIV infection to AIDS. In addition this organism can be detected in the blood and joints of patients with rheumatoid arthritis.
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General Information: Mycoplasma crocodyli was isolated from the joint of a crocodile with exudative polyarthritis. The siblingspecies of M. crocodyli, Mycoplasma alligatoris causes acute lethalprimary infection of susceptible hosts, notably American alligators.This pathogen is studied to understand the mechanisms and evolutionaryorigins of that virulence. A genome survey indicated that M. alligatorisuses sialidase (Nanl) and hyaluronidase (NagH) to generate fuel forglycolysis from host cell glycans. M. crocodyli, which does not causedisease in American alligators, possesses NagH but not Nanl, so damageto the host's extracellular matrix alone cannot explain the particularvirulence of M. alligatoris.